It also depends on how crazy your trying to go - A trailer would be a good option for a 4'x4' machine. You can pickup from most major trucking terminals (Pre Covid - Several do not allow it anymore) You can go that route & Call ahead. Grab a box truck from Penske with a lift Gate & you should be good to go. Most Moving box trucks have a ramp available as well if you dont want to spend $500 +, But its very limited on Size & Weight. Moved our First UV Printer this way.
If your looking at a larger machine than a tow motor would be a great option, We had a heavy lift tow motor brought in & it cost us $800 for two days. Well worth the peace of mind when dealing with heavy equipment & Ensuring no one gets hurt.
You can also try to work with a local shipper & See if its possible to uncrate your machine on there site - This was possible before Covid now many places are more strict on onsite visitors.
I would find the best route and make sure to not cheap out on this part - The worst thing to do is to damage a brand new machine dragging it off a truck or having someone get hurt.