Hand cutting joinery is one of the most rewarding activities. For dovetails I involve the table saw and the bandsaw a little but mostly it's a process of layout, sawing and chopping, followed by glue up , trimming and finishing. I'm in no hurry and refining the steps is satisfying.
Box joints are different. They seem like such a natural fit for table saw or router that I always go to one or the other. But it's always a struggle to get accurate and consistent results. I have made and had poor results with a few jigs over the years and usually think it would have been easier to cut them by hand. I should cut a set or two just for practice.