I pre-painted the OSB I put up in my shop. I put a coat of oil based primer on (KILZ) the coated with the latex paint. I liked the results. I needed a small piece to finish the job and just coated it with the latex paint. The latex paint only panel seemed to lift some of the thinner pieces and wasn't nearly as smooth as the oil based primer sheets. Not sure if this is typical, just my experience. I did put it on with a roller and it worked fine.