My Delta drill press has never gotten rough handling, but run-out seems to be a problem. Most noticeable when I need a Forstner hole in a particular place, the wobble transmits to the project. Sometimes the hole edges look sloppy.
In the attached photo, the quill is extended after I removed, cleaned and re-seated the Morse taper. The painted steel rod in the chuck came from the manufacturer to set-up and check run-out. I measured run out at four places:
A - Receiver for the Morse taper (part of the quill, I guess): 1/1000
B - Top ring of the Jacobs chuck: 10/1000
C - Bottom cylinder of the Jacobs chuck: 3/1000
D - End of the test rod: 9/1000
I know woodwork isn't as precise as metalwork, and I don't know whether my expectations are fair, but 9/1000 seems a lot when it's rattling the project piece around. I also don't know how to understand the small run-out at C, with large run-out at B and D.