I normally use the liquid craft paint but in this example I sprayed the clear acrylic with red Krylon then reverse engraved the images. I then filled the yellow areas with liquid craft paint using a card, then sprayed the entire back with white Krylon. I then covered the back with white vinyl as it was used outdoors in a restaurants roof top garden.
I should add that the quality of the sign is far better than the quality of the picture.
painted acrylic.jpg