How much "better" of a cyclone are you set on?
I run my 5hp ClearVue cyclone with 6" PVC ducts. It is apparently designed for 6" ducts and comes with a 6" inlet port from the factory. The longest run in my shop is over 40'. In my opinion the performance is incredible. (I do use 4" ducts on some machines and sometimes connect smaller tools with a shop vac hose.)
I can't imagine needing a more powerful cyclone with larger ductwork unless perhaps in a shop where more then one chip-spewing machine is running at the same time.
Here is something from ClearVue to read about ductwork:
https://www.clearvuecyclones.com/content/6-duct-design
JKJ