Lee Schierer
USNA '71
Go Navy!
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Absolutely. If you make closely fitted drawers of lumber acclimated to 50-60% rh and put them in a consistent 40% rh atmosphere you're likely to have problems. You need to get the mc lower before building or fit the drawers more loosely. Simply stress relieving the lumber and acclimating it in a shop with high rh is not going to forestall movement in service.
Around here, if a drawer doesn't rattle in the winter, it doesn't open in the summer. We can get desert-like indoor RH in the winter and Florida-like humidity in the summer. You just have to accommodate for it in the design. "Piston fit" drawers are a pipe dream in my climate.